impac2t beschäftigt sich mit der Frage, wie die pharmazeutische Expertise dem Patienten und der Gesellschaft besseren Nutzen bringt.

Unsere Mind Map der Forschungsschwerpunkte:

Schwerpunkt

Projekt

Inhalte

Veröffentlichungen

Medikations-management

Die WestGEM Studie

• Wirksamkeitsstudie

• Patientenselektion

• Akzeptanz

• Einnahmeverhalten

• Zusammenarbeit

>Köberlein-Neu J, et al.: Interprofessional medication management in patients with multiple morbidities—a cluster-randomized trial (the WestGem stud>y). DtschArztebl Int 2016; 113: 741–8. >Rose O, et al. Priority Setting and Influential Factors on Acceptance of Pharmaceutical Recommendations in Collaborative Medication Reviews in an Ambulatory Care Setting – Analysis of a Cluster Randomized Controlled Trial (WestGem-Study). PLoS One. 2016 Jun 2;11(6):e0156304. >Rose O, et al. Patient selection and general practitioners‘ perception of collaboration in medication review. Res Social Adm Pharm. 2019 May;15(5):521-527.>Rose O, et al. Discrepancies between home medication and patient documentation in primary care. Res Social Adm Pharm. 2018 Apr;14(4):340-346.

Die AMBER Studie

• Ein Algorithmus für das Medikationsmanagement

• Befragungen, 3 systematische reviews, Delphi survey, Testung

>Erzkamp S, Rose O. Development and evaluation of an algorithm-based tool for Medication Management in nursing homes: the AMBER study protocol. BMJ Open. 2018;8(4):e019398.>Erzkamp S, Köberlein-Neu J, Rose O. An Algorithm for Comprehensive Medication Management in Nursing Homes: Results of the AMBER Project. Drug Saf. 2020 Oct 31.

Standards im Medikations-management

• Internationale Standards für das Medikationsmanagement

>Rose, O. et al. Standards in medication review: An international perspective. Canadian Pharmacists Journal, 153(4), 215–223.

Pharmaceutical care Network Europe (PCNE ) Klassifikation arzneimittelbezogener Probleme

• Validierung

>Schindler E, Richling I, Rose O. Pharmaceutical Care Network Europe (PCNE) drug-related problem classification version 9.00: German translation and validation. Int J Clin Pharm. 2021 Jun;43(3):726-730. 

Vergleich verschiedener PIM-Listen

• Testung auf Station

>Kerliu L, Citaku D, Rudhani I, Hughes JD, Rose O, Hoti K. Exploring instruments used to evaluate potentially inappropriate medication use in hospitalised elderly patients in Kosovo. Eur J Hosp Pharm. 2021;28(4):223-228. 

Parkinson

Parkinsonnetz Münsterland +

• Aufbau eines Parkinsonnetzes unter pharmazeutischer Beteiligung

>Rose O, et al. Enhancing medication therapy in Parkinson’s disease by establishing an interprofessional network including pharmacists. Int J Clin Pharm. 2021;43(3):441-448.>Rose O, et al. Enhancing medication therapy in Parkinson’s disease by establishing an interprofessional network including pharmacists. Int J Clin Pharm. 2021 Jun;43(3):441-448.

Levodopa-Generikawechsel

• Effekte eines Generikawechsels am Beispiel von Levodopa

• Systematischer Review, Patientenbefragung, Dissolution

>Weitzel J, et al. Effects of generic exchange of solid oral dosage forms in neurological disorders: a systematic review. Int J Clin Pharm. 2020;42(2):393-417. >Weitzel J, Langer K, Rose O. Effects of Generic Exchange of Levodopa Medication in Patients With Parkinson Disease. J Patient Saf. 2022 Oct 1;18(7):704-710.>Weitzel J, et al. Different dissolution conditions affect stability and dissolution profiles of bioequivalent levodopa-containing oral dosage forms. Int J Pharm. 2022 Dec 15;629:122401. 

Professioneller Wandel und translationale Forschung

Entwicklung der Pharmakotherapie

• Internationaler Vergleich der Entwicklung der Curricula und klinischer Tätigkeiten

>Rose O, et al. Development of clinical pharmacy services in Australia, Austria, Belgium, Bosnia-Herzegovina, Canada, Germany, Japan, Kosovo, Switzerland, the Netherlands, Thailand, USA and correlation with educational standards, level of research, and implemen. Int J Clin Pharmacol Ther. 2018 Nov;56(11):518-530. 

3D Druck in Apotheken

• A business model framework

>Feldmann C, Rose O. Additive manufacturing in community pharmacies: a framework for business model innovation. BMJ Innovations. Published Online First: 16 March 2021. 

COVID-19 Impfungen in Apotheken

• Patient and provider satisfaction

>Rose O, et al. COVID-19 vaccinations in German pharmacies: A survey on patient and provider satisfaction. Vaccine. 2022 Aug 19;40(35):5207-5212. 

COVID-19 Testungen in Apotheken

• Eine Strategie für Deutschland

>In Veröffentlichung